The word “despair” is overused and banalized now, but it’s a serious word, and I’m using it seriously. It’s close to what people call dread or angst, but it’s not these things, quite. It’s more like wanting to die in order to escape the unbearable sadness of knowing I’m small and weak and selfish and going, without doubt, to die. It’s wanting to jump overboard.
– David Foster Wallace in Shippin Out